Phone: (716) 878-5114
M.S., Seoul National
University, Seoul, Korea, 1990
Ph.D., Texas A&M University, College Station, TX, 1999
My reaching courses include General Chemistry I and II (CHE111 and CHE112), Analytical Chemistry (CHE301), Literature in Chemistry (CHE310), Optical Microscopy (FOR416), Advanced Analytical Chemistry (CHE680), Scientific Criminal Evidence Analysis (FOR122), Forensic Chemistry Laboratory (FOR414W), Forensic Applications of Instrumental Analysis (FOR614), and Microscopy in Forensic Science (FOR616).
Currently, forensic analytical chemistry covers many facets of forensic science, including drug analysis, toxicology, trace analysis, arson analysis, and DNA/serology. As a part of forensic analytical chemistry, drug analysis – the detection and identification of illicit substances – is of significance in law enforcement and criminal investigations. According to the Compendium of Federal Justice Statistics, drug prosecutions have comprised an increasing proportion of the Federal criminal caseload – from 21% of defendants during 1982 to 35% during 2002. These statistics demonstrate that the role played by forensic drug analysis is becoming greater than in the past and more professionals with a forensic background are needed. In fact, the American Academy of Forensic Sciences (AAFS) estimates that there will be about 10,000 new job openings in forensic science in the next decade.
My current research includes the optimization/improvement of conventional analytical techniques using gas chromatography/mass spectrometry (GC/MS), high-performance liquid chromatography (HPLC), Fourier-transform infrared spectrometry (FTIR), and ultraviolet/visible spectrometry (UV/Vis). Emphasis will be placed on the optimization and improvement of these techniques to increase sensitivity and selectivity toward target drugs and the training of undergraduate (or graduate) students.
My second project focuses on the development of novel protein array-based devices as portable sensors for drug detection. In this project, protein-arrays will be prepared by microfabrication techniques and surface chemistry; their drug detection capability will then be evaluated and compared to that of conventional techniques, such as spot tests. Any students working in my laboratory are expected to obtain various chemical and analytical techniques including followings:
1. Analysis of natural products, food additives, illegal drug compounds and their metabolites, and organic volatiles using gas chromatography (GC), gas chromatography-mass spectrometry (GC/MS), and high-performance liquid chromatography (HPLC) (see more)
2. Preparation, modification, and characterization of organic self-assembled monolayers (SAMs) on silicon, silicon oxide, and gold substrates (see more)
3. Preparation of protein arrays using microcontact printing and photolithography (see more)
I have summarized my results and details can be found in the liked websites. For my research, a couple of analytical instruments are available in my lab. These are Agilent 6890 GC with Dual FID, Agilent 1260 HPLC system with DAD, Thermo Nicolet Magna 860 FTIR spectrometer equipped with MCTA detector and VeeMax II sample stage, Agilent 8453 Diode Array UV/Vis Spectrophotometer, and Shimadzu UV 2101 PC Scanning UV/Vis Spectrophotometer. In addition, our research group utilizes analytical instruments in Chemistry Department including Agilent 7890/5975 MSD, Raman Microscope, Thermo Exactive Orbitrap LC-MS, etc.
Research Group (meet group members)
Research opportunities for undergraduate and graduate students are available. I believe students joining my research project will benefit from learning novel and standard analytical techniques and procedures, handling materials, reviewing literature, and the critical thinking involved in the completion of these projects. You will gain experience that would otherwise be unavailable in a typical laboratory course. I believe this project will provide a wonderful opportunity for you who plan to pursue careers in forensic chemistry, pharmaceutical chemistry, biomedical science, or environmental science. Currently, two undergraduate students are in my research group. If you are interested in, contact me via email or 716-878-5114.
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